“In this review, the catalogue of SLE susceptibility loci will be updated, and biological signatures implicated by the SLE-risk variants will be critically discussed. It is optimistically hoped that identification of SLE risk variants will enable the prognostic and therapeutic biomarker armamentarium of SLE to be strengthened, a major leap towards precision medicine in the management of the condition.”
Sehwan and Young-Chang are joint co-first authors; Kwangwoo and Prof. Mak at NUS contributed equally as corresponding authors on this manuscript.